Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 12 findings · 6 reviews · Headline outcomes only

No studies found 9 · 75%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 8.3%Moderate 1 · 8.3%High 1 · 8.3%

ALK inhibitor vs any cytotoxic chemotherapy

Health‐related quality of life: time to deterioration in composite endpoint (cough, dyspnoea, and chest pain) · advanced anaplastic lymphoma kinase (ALK)‐rearranged non‐small cell lung cancer

ALK inhibitor leads to lower health‐related quality of life: time to deterioration in composite… compared with any cytotoxic chemotherapy (high certainty).

1 finding from 1 review