Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

Capecitabine‐containing regimens vs chemotherapy regimens without capecitabine

Hand‐foot syndrome · neoadjuvant treatment of ER‐positive vs ER‐negative breast cancer

Capecitabine‐containing regimens probably leads to higher hand‐foot syndrome compared with non‐capecitabine‐containing regimens (moderate certainty).

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
OR 6.77 [4.89, 9.38]
5 studies · 3021 participants
Moderate

Capecitabine‐containing regimens vs non‐capecitabine‐containing regimens or no chemotherapy

Hand‐foot syndrome · patients with early breast cancer

Capecitabine‐containing regimens probably leads to higher hand‐foot syndrome compared with non‐capecitabine‐containing regimens or no chemotherapy (moderate certainty).

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
OR 13.6 [10.65, 17.37]
8 studies · 11207 participants
Moderate