What do systematic reviews say?

5 questions · 5 findings · 1 reviews · HIV/AIDS

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 20%Moderate 4 · 80%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- An extended antiretroviral regimen administered to mothers for 28 weeks vs 1 week of antiretroviral prophylaxis · HIV transmission or death at 28 weeks among those whose diagnostic test was negative at 2 weeks
  Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
  RR 0.61 [0.38, 0.96]
  1 study · 1435 participants
  Moderate
Direct match · question page
- An extended NVP regimen administered to infants for 28 weeks vs 1 week of antiretroviral prophylaxis · HIV transmission or death at 28 weeks among those whose diagnostic test was negative at 2 weeks
  Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
  RR 0.38 [0.22, 0.65]
  1 study · 1447 participants
  Moderate
Direct match · question page
- An extended antiretroviral regimen administered to mothers for 28 weeks vs an extended NVP regimen administered to infants · HIV transmission or death at 28 weeks among those whose diagnostic test was negative at 2 weeks
  Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
  RR 1.6 [0.91, 2.82]
  1 study · 1618 participants
  Moderate
Related · question page
- An extended ZDV/3TC/LPV/r regimen administered to mothers vs short course ZDV (intrapartum ZDV/3TC/sdNVP) · HIV transmission or Death at 12 months among those whose HIV diagnostic testing was negative at 6 weeks after birth
  Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
  HR 0.52 [0.28, 0.93]
  1 study · 599 participants
  Moderate
Related · question page
- An extended ZDV/3TC/LPV/r regimen administered to mothers vs short course ZDV (intrapartum ZDV/3TC/sdNVP) · HIV transmission or Death at 6 months among those whose HIV diagnostic testing was negative at 6 weeks after birth
  Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
  HR 0.61 [0.3, 1.24]
  1 study · 599 participants
  Low

An extended antiretroviral regimen administered to mothers for 28 weeks vs 1 week of antiretroviral prophylaxis

HIV transmission or death at 28 weeks among those whose diagnostic test was negative at 2 weeks · HIV‐infected mothers and their breastfeeding infants

An extended antiretroviral regimen administered to mothers for 28… probably leads to lower HIV transmission or death at 28 weeks among those whose diagnostic… compared with 1 week of antiretroviral prophylaxis (moderate certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
RR 0.61 [0.38, 0.96]
1 study · 1435 participants
Moderate

An extended NVP regimen administered to infants for 28 weeks vs 1 week of antiretroviral prophylaxis

HIV transmission or death at 28 weeks among those whose diagnostic test was negative at 2 weeks · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 28 weeks probably leads to lower HIV transmission or death at 28 weeks among those whose diagnostic… compared with 1 week of antiretroviral prophylaxis (moderate certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
RR 0.38 [0.22, 0.65]
1 study · 1447 participants
Moderate

An extended antiretroviral regimen administered to mothers for 28 weeks vs an extended NVP regimen administered to infants

HIV transmission or death at 28 weeks among those whose diagnostic test was negative at 2 weeks · HIV‐infected mothers and their breastfeeding infants

An extended antiretroviral regimen administered to mothers for 28… showed no clear difference in HIV transmission or death at 28 weeks among those whose diagnostic… compared with an extended NVP regimen administered to infants (moderate certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
RR 1.6 [0.91, 2.82]
1 study · 1618 participants
Moderate

An extended ZDV/3TC/LPV/r regimen administered to mothers vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

HIV transmission or Death at 6 months among those whose HIV diagnostic testing was negative at 6 weeks after birth · HIV‐infected mothers and their breastfeeding infants

An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in HIV transmission or Death at 6 months among those whose HIV… compared with short course ZDV (intrapartum ZDV/3TC/sdNVP) (low certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
HR 0.61 [0.3, 1.24]
1 study · 599 participants
Low

An extended ZDV/3TC/LPV/r regimen administered to mothers vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

HIV transmission or death at 12 months among all infants whose HIV diagnostic testing was negative within 6 weeks of birth · HIV‐infected mothers and their breastfeeding infants

An extended ZDV/3TC/LPV/r regimen administered to mothers probably leads to lower HIV transmission or Death at 12 months among those whose HIV… compared with short course ZDV (intrapartum ZDV/3TC/sdNVP) (moderate certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
HR 0.52 [0.28, 0.93]
1 study · 599 participants
Moderate