Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 9 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 33.3%Moderate 6 · 66.7%High 0 · 0%

Low dose CNI calcineurin inhibitor (CNI) + mammalian target of rapamycin inhibitor (mTORi) vs standard dose CNI

Graft loss · kidney transplant recipients

Low dose CNI calcineurin inhibitor (CNI) + mammalian target of… showed no clear difference in graft loss compared with standard dose CNI (moderate certainty).

1 finding from 1 review

Calcineurin inhibitor (CNI) avoidance and late CNI withdrawal vs standard dose CNI

Graft loss: late withdrawal · kidney transplant recipients

Calcineurin inhibitor (CNI) avoidance and late CNI withdrawal probably leads to lower graft loss: late withdrawal compared with standard dose CNI (moderate certainty).

1 finding from 1 review

Calcineurin inhibitor (CNI) avoidance and late withdrawal with mammalian target of rapamycin inhibitor (mTORi) vs standard dose CNI

Graft loss: avoidance · kidney transplant recipients

Calcineurin inhibitor (CNI) avoidance and late withdrawal with… showed no clear difference in graft loss: avoidance compared with standard dose CNI (moderate certainty).

1 finding from 1 review

Calcineurin inhibitor (CNI) avoidance and late withdrawal with mammalian target of rapamycin inhibitor (mTORi) vs standard dose CNI

Graft loss: late withdrawal · kidney transplant recipients

Calcineurin inhibitor (CNI) avoidance and late withdrawal with… showed no clear difference in graft loss: late withdrawal compared with standard dose CNI (moderate certainty).

1 finding from 1 review

Target of rapamycin inhibitors (TOR‐I) vs calcineurin inhibitors (CNI): main outcomes

Graft loss censored for death · primary immunosuppression in kidney transplant recipients

Target of rapamycin inhibitors (TOR‐I) showed no clear difference in graft loss censored for death compared with calcineurin inhibitors (CNI): main outcomes (moderate certainty).

1 finding from 1 review