Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews · Schizophrenia

No studies found 0 · 0%GRADE not reported 1 · 33.3%Very low 1 · 33.3%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Any antiglucocorticoid vs placebo

Global state: 1. General ‐ no clinically significant improvement ‐ short term < 30% improvement on BPRS · people with psychosis

Any antiglucocorticoid may leads to lower global state: 1. General ‐ no clinically significant improvement ‐… compared with placebo (low certainty).

1 finding from 1 review

Any antiglucocorticoid vs placebo

Global state: general ‐no clinically significant improvement ‐ data only for mifepristone < 30% improvement on BPRS · people with psychosis

It is very uncertain whether any antiglucocorticoid changes global state: general ‐no clinically significant improvement ‐ data… compared with placebo (very low certainty).

1 finding from 1 review