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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews · Cystic Fibrosis and Genetic Disorders

No studies found 2 · 40%GRADE not reported 0 · 0%Very low 3 · 60%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Vitamin C 1400 mg plus vitamin E 800 mg vs placebo

Acute chest syndrome ( · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)

It is very uncertain whether vitamin C 1400 mg plus vitamin E 800 mg changes frequency of sickle cell‐related complications: acute chest syndrome compared with placebo (very low certainty).

1 finding from 1 review

Zinc vs placebo

Frequency of sickle cell‐related complications: number of participants with completely healed leg ulcer ( · people with sickle cell disease

It is very uncertain whether zinc changes frequency of sickle cell‐related complications: number of… compared with placebo (very low certainty).

1 finding from 1 review