Evidence Gaps

What do systematic reviews say?

1 questions · 3 findings · 1 reviews · Acute Respiratory Infections

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Final diagnosis of at least one episode of AOM · preventing acute otitis media in children up to 12 years of age

Xylitol probably leads to lower final diagnosis of at least one episode of AOM compared with control (moderate certainty).

3 findings from 1 review

Xylitol for preventing acute otitis media in children up to 12 years of age 2016 · Cochrane Headline outcomes only
RR 0.75 [0.65, 0.88]
3 studies · 1826 participants
Moderate
Xylitol for preventing acute otitis media in children up to 12 years of age 2016 · Cochrane Headline outcomes only
RR 0.9 [0.67, 1.21]
1 study · 326 participants
Low
Xylitol for preventing acute otitis media in children up to 12 years of age 2016 · Cochrane Headline outcomes only
RR 1.13 [0.83, 1.53]
1 study · 1253 participants
Moderate