Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 1 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

Adalimumab vs active comparators

Failure to maintain clinical or endoscopic response with prior TNF‐α antagonist exposure · People with quiescent Crohn's disease (ileocolic resection)

The review found no eligible studies for this question.

1 finding from 1 review

Adalimumab for maintenance of remission in Crohn's disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adalimumab vs placebo

Failure to maintain clinical or endoscopic response with prior TNF‐α antagonist exposure · Participants with Crohn's disease in remission

Adalimumab probably leads to lower failure to maintain clinical or endoscopic response with prior TNF‐α… compared with placebo (moderate certainty).

1 finding from 1 review

Adalimumab for maintenance of remission in Crohn's disease 2020 · Cochrane Headline outcomes only
RR 0.76 [0.68, 0.85]
2 studies · 302 participants
Moderate