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Evidence found and GRADE certainty

2 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 75%High 1 · 25%

Two infusions of natalizumab (6 mg/kg) vs placebo

Failure to induce remission at 6 weeks · Patients with active Crohn's disease

Two infusions of natalizumab (6 mg/kg) showed no clear difference in failure to induce remission at 6 weeks compared with placebo (moderate certainty).

2 findings from 1 review

Two infusions of natalizumab (300 mg or 3 mg/kg) vs placebo

Failure to induce remission at 6 weeks · Patients with active Crohn's disease

Two infusions of natalizumab (300 mg or 3 mg/kg) leads to lower failure to induce remission at 6 weeks compared with placebo (high certainty).

2 findings from 1 review