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Evidence found and GRADE certainty

14 questions · 15 findings · 2 reviews · Headline outcomes only

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No studies found 4 · 26.7%GRADE not reported 0 · 0%Very low 5 · 33.3%Low 2 · 13.3%Moderate 4 · 26.7%High 0 · 0%

Comparison 2: 2 days oral amoxicillin + injectable gentamicin followed by 5 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Early neonatal mortality · neonates with possible serious bacterial infection

The review found no eligible studies for this question.

1 finding from 1 review

Comparison 2: 2 days injectable benzylpenicillin + injectable gentamicin followed by 5 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Early neonatal mortality · neonates with possible serious bacterial infection

The review found no eligible studies for this question.

1 finding from 1 review

Comparison 1: community‐based antibiotic delivery vs usual care

Early neonatal mortality · neonates with sepsis

Comparison 1: community‐based antibiotic delivery probably leads to lower early neonatal mortality compared with standard care (moderate certainty).

1 finding from 1 review

Community health educational interventions vs control

Early neonatal mortality · developing countries

It is very uncertain whether community health educational interventions changes early neonatal mortality compared with control (very low certainty).

2 findings from 1 review

Community health educational one‐to‐one and group and both counselling (subgroup) vs control

Early neonatal mortality ‐ Group counselling · developing countries

Community health educational one‐to‐one and group and both… may leads to lower early neonatal mortality ‐ Group counselling compared with control (low certainty).

1 finding from 1 review

Community health educational one‐to‐one and group and both counselling (subgroup) vs control

Early neonatal mortality ‐ One‐to‐one counselling · developing countries

Community health educational one‐to‐one and group and both… may leads to higher early neonatal mortality ‐ One‐to‐one counselling compared with control (low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Early neonatal mortality ‐ Intervention given to mothers only · developing countries

It is very uncertain whether community health educational intervention for family members and… changes early neonatal mortality ‐ Intervention given to mothers only compared with control (very low certainty).

1 finding from 1 review

Community health educational one‐to‐one and group and both counselling (subgroup) vs control

Early neonatal mortality ‐ Both one‐to‐one and group counselling · developing countries

Community health educational one‐to‐one and group and both… probably leads to lower early neonatal mortality ‐ Both one‐to‐one and group counselling compared with control (moderate certainty).

1 finding from 1 review

Community health educational ANC period and PNC period and both periods (subgroup) vs control

Early neonatal mortality ‐ Education provided during ANC period only · developing countries

It is very uncertain whether community health educational ANC period and PNC period and both… changes early neonatal mortality ‐ Education provided during ANC period only compared with control (very low certainty).

1 finding from 1 review

Community health educational ANC period and PNC period and both periods (subgroup) vs control

Early neonatal mortality ‐ Education provided during PNC period only · developing countries

Community health educational ANC period and PNC period and both… showed no clear difference in early neonatal mortality ‐ Education provided during PNC period only compared with control (moderate certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Early neonatal mortality ‐ Intervention given to mothers and family members · developing countries

It is very uncertain whether community health educational intervention for family members and… changes early neonatal mortality ‐ Intervention given to mothers and family… compared with control (very low certainty).

1 finding from 1 review

Community health educational ANC period and PNC period and both periods (subgroup) vs control

Early neonatal mortality ‐ Education provided during both ANC and PNC periods · developing countries

It is very uncertain whether community health educational ANC period and PNC period and both… changes early neonatal mortality ‐ Education provided during both ANC and… compared with control (very low certainty).

1 finding from 1 review