What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Oral Health

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No studies found 0 · 0%GRADE not reported 4 · 66.7%Very low 1 · 16.7%Low 1 · 16.7%Moderate 0 · 0%High 0 · 0%

Triclosan rinse vs Saline rinse

Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU

Triclosan rinse led to lower duration of ICU stay compared with saline rinse; GRADE not reported.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
MD -4.97 [-5.55, -4.39]
1 study · 324 participants
GRADE not reported

Saline rinse vs usual or supportive care

Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU

Saline rinse showed no clear difference in duration of ICU stay compared with usual care (no rinse); GRADE not reported.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
MD -1.17 [-3.95, 1.60]
2 studies · 324 participants
GRADE not reported

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Duration of ICU stay · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in duration of ICU stay compared with placebo or usual care (low certainty).

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Follow-up: mean 1 month
MD -0.89 [-3.59, 1.82]
5 studies · 627 participants
Low

Powered toothbrushing (as part of comprehensive oral care) vs Manual toothbrushing

Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU

Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in duration of ICU stay compared with manual toothbrushing (standard oral care); GRADE not reported.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
MD -2.00 [-5.93, 1.93]
1 study · 78 participants
GRADE not reported

Povidone iodine rinse vs Saline rinse or placebo

Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU

Povidone iodine rinse showed no clear difference in duration of ICU stay compared with saline rinse or placebo; GRADE not reported.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
MD -0.35 [-3.90, 3.21]
2 studies · 217 participants
GRADE not reported

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Duration of ICU stay · Critically ill adults receiving mechanical ventilation in ICU

It is very uncertain whether toothbrushing (with or without antiseptics), as part of oral hygiene… changes duration of ICU stay compared with no toothbrushing (with or without antiseptics) (very low certainty).

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Follow-up: mean 1 month
MD -1.89 [-3.52, -0.27]
3 studies · 749 participants
Very low