Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Drugs and Alcohol

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 100%High 0 · 0%

Leaving the study early · patients with the treatment of cocaine dependence

Any dopamine agonist showed no clear difference in dropouts compared with placebo (moderate certainty).

1 finding from 1 review

Dopamine agonists for the treatment of cocaine dependence 2015 · Cochrane Headline outcomes only
RR 1.04 [0.94, 1.14]
20 studies · 1656 participants
Moderate

Leaving the study early · patients with the treatment of cocaine dependence

Amantidine showed no clear difference in dropouts compared with antidepressants (moderate certainty).

1 finding from 1 review

Dopamine agonists for the treatment of cocaine dependence 2015 · Cochrane Headline outcomes only
RR 0.86 [0.48, 1.53]
4 studies · 153 participants
Moderate

Leaving the study early · patients with the treatment of cocaine dependence

Amantadine showed no clear difference in dropouts compared with placebo (moderate certainty).

1 finding from 1 review

Dopamine agonists for the treatment of cocaine dependence 2015 · Cochrane Headline outcomes only
RR 0.98 [0.77, 1.26]
9 studies · 484 participants
Moderate