Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 1 · 50%

Single inhaler therapy vs fixed dose ICS

Withdrawals due to adverse events · adults with asthma not well controlled on ICS

Single inhaler therapy leads to lower discontinuation due to adverse events compared with fixed dose ICS (high certainty).

1 finding from 1 review

Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including… 2013 · Cochrane Headline outcomes only
OR 0.57 [0.35, 0.93]
2 studies · 2586 participants
High

160/4.5 mcg BDF single inhaler therapy vs current best practice

Withdrawals due to adverse events · adults with asthma not well controlled on ICS

160/4.5 mcg BDF single inhaler therapy probably leads to higher discontinuation due to adverse events compared with current best practice (moderate certainty).

1 finding from 1 review

Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including… 2013 · Cochrane Headline outcomes only
OR 2.85 [1.89, 4.3]
7 studies · 8411 participants
Moderate