What do systematic reviews say?

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found

Occlusal splint vs Pharmacological therapy

The review found no eligible studies for this question.

• Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes
  Listed in Summary of findings 6 as 'Not reported'; this outcome was not reported by any included study for this comparison.
  0 studies
  No studies found

Occlusal splint vs No treatment or placebo (non-occlusal or transparent-foil placebo splint)

The review found no eligible studies for this question.

• Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes
  Listed in Summary of findings 1 as 'Not reported'; this outcome was not reported by any included study for this comparison. Discomfort was not reported in any included study across the whole review.
  0 studies
  No studies found

Occlusal splint vs acupuncture

The review found no eligible studies for this question.

• Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes
  Listed in Summary of findings 5 as 'Not reported'; this outcome was not reported by any included study for this comparison.
  0 studies
  No studies found

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

The review found no eligible studies for this question.

• Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes
  Listed in Summary of findings 3 as 'Not reported'; this outcome was not reported by any included study for this comparison.
  0 studies
  No studies found

Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)

The review found no eligible studies for this question.

• Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes
  Listed in Summary of findings 4 as 'Not reported'; this outcome was not reported by any included study for this comparison.
  0 studies
  No studies found

Occlusal splint vs Another occlusal splint with a different mechanism of action

The review found no eligible studies for this question.

• Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes
  Listed in Summary of findings 2 as 'Not reported'; this outcome was not reported by any included study for this comparison.
  0 studies
  No studies found

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

• Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes

  Evening after extraction and one week later
  Self-reported VAS pain (Naoumova 2012): pain and discomfort from extraction of the primary canine were low both during and after the procedure and mostly absent at one week; 35% of boys and 50% of girls took one dose…
  1 study · 44 participants
  GRADE not reported

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

The review found no eligible studies for this question.

• Interventions for treating post‐extraction bleeding 2018 · Cochrane All outcomes
  No data are available as no RCTs have been conducted on interventions to treat post-extraction bleeding
  0 studies
  No studies found

Hall technique vs Conventional restoration

The reported estimate for treatment discomfort with the Hall Technique versus conventional restorations was inconclusive (ungraded).

• Minimal intervention dentistry for managing carious lesions into dentine in primary teeth: an umbrella review. 2022 All outcomes

  During treatment
  RR 1.67 [0.65, 4.25]
  2 studies
  GRADE not reported

Atraumatic restorative treatment vs Conventional treatment with local anaesthesia

The reported estimate for discomfort with ART versus conventional treatment was inconclusive (ungraded).

• Minimal intervention dentistry for managing carious lesions into dentine in primary teeth: an umbrella review. 2022 All outcomes

  During procedure · Children 6-8 years; ART vs conventional treatment with local anaesthetic
  OR 0.95 [0.51, 1.79]
  6 studies · 1107 participants
  GRADE not reported

LongoVital (herbal component alone) vs placebo

LongoVital (herbal component alone) showed no clear difference in general degree of discomfort compared with placebo; GRADE not reported.

• Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes

  4 to 6 months
  MD -0.30 [-0.37, 0.97]
  1 study · 50 participants
  GRADE not reported

Antioxidants (lycopene, curcumin, Oxitard) vs Placebo or no active treatment

The review found no eligible studies for this question.

• Interventions for managing oral submucous fibrosis 2024 · Cochrane All outcomes
  The trials did not measure postoperative discomfort or pain.
  0 studies
  No studies found

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

• Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes

  6 months
  Included study (Hoang 2012) reported there were no adverse effects
  1 study · 30 participants
  Very low

ARP with allograft (bone graft) vs ARP with xenograft

• Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes

  6 months
  1 trial (Scheyer 2016) reported moderate glazing, redness and oedema, while 2 trials (Santana 2019; Serrano Mendez 2017) reported there were no adverse events
  3 studies · 87 participants
  Low

ARP with xenograft (bone graft) vs Extraction alone

• Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes

  6 to 36 months
  1 trial (Cha 2019) reported delayed healing with partial exposure of the buccal plate at suture removal by 1 participant in the test group; another trial (Festa 2013) reported pain and swelling
  2 studies · 54 participants
  Low

ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane

• Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes

  9 months
  Fibrous adhesions at the cervical part of previously preserved sockets were observed in 2 participants (Brkovic 2012)
  1 study · 20 participants
  Very low

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

• Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes

  6 months
  Included study (Fernandes 2011) reported there were no adverse effects
  1 study · 18 participants
  Very low

ARP with alloplast vs Extraction alone

• Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes

  6 months
  Included study (Madan 2014) reported there were no adverse effects
  1 study · 15 participants
  Very low

ARP with alloplast vs ARP with xenograft

• Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes

  6 to 8 months
  1 trial (Patel 2013) reported pain, swelling, membrane exposure and partial loss of grafting material, while the other trial (Gholami 2012) reported that the procedure was uneventful
  2 studies · 37 participants
  Low