Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Emergency and Critical Care

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No studies found 1 · 25%GRADE not reported 0 · 0%Very low 1 · 25%Low 1 · 25%Moderate 1 · 25%High 0 · 0%

Intravenous midazolam vs placebo

Discomfort/pain · adults requiring sedation before gastrointestinal endoscopy and bronchoscopy

1 finding from 1 review

Midazolam for sedation before procedures 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 167 participants
Very low

Oral midazolam vs placebo

Discomfort/pain · children requiring sedation before micturating cystourethrograms and Kirschner wire removal and adults undergoing flexible sigmoidoscopy

1 finding from 1 review

Midazolam for sedation before procedures 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 99 participants
Moderate

Summary of findings ‐ Intranasal midazolam vs placebo

Discomfort/pain · Children requiring sedation before voiding cystourethrograms and adults undergoing MRI

The review found no eligible studies for this question.

1 finding from 1 review

Midazolam for sedation before procedures 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intravenous midazolam vs diazepam

Discomfort/pain · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy

Intravenous midazolam showed no clear difference in discomfort/pain compared with diazepam (low certainty).

1 finding from 1 review

Midazolam for sedation before procedures 2016 · Cochrane Headline outcomes only
RR 0.6 [0.24, 1.49]
5 studies · 415 participants
Low