Findings

What do systematic reviews say?

8 questions · 8 findings · 2 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 12.5%Low 7 · 87.5%Moderate 0 · 0%High 0 · 0%

Diarrhoea grade 4 · participants with cancer treated with chemotherapy

Probiotics showed no clear difference in diarrhoea grade 4 compared with placebo (low certainty).

1 finding from 1 review

Diarrhoea grade 4 · participants with cancer treated with radiotherapy (with or without chemotherapy)

1 finding from 1 review

Diarrhoea (grade 2+) · participants with cancer treated with chemotherapy

Probiotics showed no clear difference in diarrhoea grade 2 or higher compared with placebo (low certainty).

1 finding from 1 review

Grade 3 to 4 diarrhoea · participants with cancer treated with chemotherapy

Probiotics showed no clear difference in diarrhoea grade 3 or higher compared with placebo (low certainty).

1 finding from 1 review

Diarrhoea (grade 2+) · participants with cancer treated with radiotherapy (with or without chemotherapy)

Probiotics showed no clear difference in diarrhoea grade 2 or higher compared with placebo (low certainty).

1 finding from 1 review

Grade 3 to 4 diarrhoea · participants with cancer treated with radiotherapy (with or without chemotherapy)

1 finding from 1 review

Grade ≥ 3 diarrhoea · participants with cancer treated with radiotherapy (with or without chemotherapy)

Probiotics may leads to lower severity of diarrhoea: grade 3 or higher compared with other active treatment (low certainty).

1 finding from 1 review

Diarrhoea (grade 2+) · People undergoing RT for pelvic cancer

Summary of findings: Probiotics may leads to lower diarrhoea (grade 2+) compared with control (placebo or no intervention) (low certainty).

1 finding from 1 review