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What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Oral alkylating agents ± steroids vs steroids or placebo or both, or no treatment

Death at final · primary membranous nephropathy in adults with nephrotic syndrome

Oral alkylating agents ± steroids showed no clear difference in death at final compared with placebo/no treatment/steroids (low certainty).

1 finding from 1 review

Calcineurin inhibitors ± steroids vs alkylating agents ± steroids

Death at final · primary membranous nephropathy in adults with nephrotic syndrome

It is very uncertain whether calcineurin inhibitors ± steroids changes death at final compared with alkylating agents ± steroids (very low certainty).

1 finding from 1 review