What do systematic reviews say?

Summary of findings table ‐ Starting short‐term prophylactic dose anticoagulation vs avoiding anticoagulation

It is very uncertain whether summary of findings table ‐ Starting short‐term prophylactic dose… changes death compared with avoiding anticoagulation (very low certainty).

• Antithrombotic treatment after stroke due to intracerebral haemorrhage 2023 · Cochrane Headline outcomes only
  RR 1 [0.59, 1.7]
  3 studies · 258 participants
  Very low

Summary of findings ‐ withdrawal of penicillin prophylaxis vs continuation

• Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 400 participants
  Low

Summary of findings ‐ initiation of penicillin prophylaxis vs placebo

Summary of findings ‐ initiation of penicillin prophylaxis showed no clear difference in deaths compared with placebo (low certainty).

• Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease 2021 · Cochrane Headline outcomes only
  OR 0.11 [0.01, 2.11]
  2 studies · 457 participants
  Low