Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

11 questions · 11 findings · 7 reviews · Headline outcomes only

No studies found 1 · 9.1%GRADE not reported 0 · 0%Very low 2 · 18.2%Low 7 · 63.6%Moderate 1 · 9.1%High 0 · 0%

Summary of findings for selective ß2‐adrenergic agonist vs no tocolytic agent, whilst awaiting emergency delivery

Perinatal death or severe morbidity · women with fetal distress for whom the decision had been made to delivery by emergency caesarean section

The review found no eligible studies for this question.

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Death · participants with UA/NSTEMI in the stent era

Routine invasive strategies showed no clear difference in death compared with selective invasive strategies (conservative) (low certainty).

1 finding from 1 review

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Death · proteinuric chronic kidney disease

Non‐steroidal mineralocorticoid receptor antagonist showed no clear difference in death compared with selective aldosterone antagonist (low certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Fatal or nonfatal myocardial infarction · participants with UA/NSTEMI in the stent era

Routine invasive strategies showed no clear difference in death or non‐fatal Myocardial infarction compared with selective invasive strategies (conservative) (low certainty).

1 finding from 1 review

Shunting vs no shunting

Stroke‐related death within 30 days of surgery (best‐case) · patients with symptomatic or asymptomatic carotid disease

Shunting may leads to lower stroke‐related death within 30 days of surgery (best‐case) compared with no shunting (low certainty).

1 finding from 1 review

Shunting vs no shunting

Stroke‐related death within 30 days of surgery (worst‐case) · patients with symptomatic or asymptomatic carotid disease

Shunting showed no clear difference in stroke‐related death within 30 days of surgery (worst‐case) compared with no shunting (low certainty).

1 finding from 1 review