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What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 3 reviews · Headline outcomes only

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No studies found 3 · 50%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 1 · 16.7%Moderate 0 · 0%High 0 · 0%

Prevention of eclampsia: IV maintenance vs a serial IV bolus regimen

Death of the baby before discharge: perinatal death · women with pre‐eclampsia

It is very uncertain whether prevention of eclampsia: maintenance regimen by continuous infusion changes death of the baby before discharge: perinatal death compared with a serial IV bolus regimen (very low certainty).

1 finding from 1 review

Continuous platinum infusion vs bolus platinum infusion

Adverse effects: toxic death (no definition provided) · children with cancer treated with platinum‐based therapy

Continuous platinum infusion showed no clear difference in adverse effects: toxic death (no definition provided) compared with bolus platinum infusion (low certainty).

1 finding from 1 review