Findings

What do systematic reviews say?

15 questions · 15 findings · 3 reviews · Neonatal

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No studies found 2 · 13.3%GRADE not reported 0 · 0%Very low 4 · 26.7%Low 8 · 53.3%Moderate 1 · 6.7%High 0 · 0%

Phenobarbital vs diazepam

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Low

Phenobarbital vs chlorpromazine

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 87 participants
Low

Phenobarbital and opioid vs opioid

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Clonidine and opioid vs opioid

Length of hospital stay · newborn infants with opioid withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Clonidine and opioid vs phenobarbital and opioid

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 91 participants
Low

Phenobarbital vs supportive care

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Very low

Morphine vs methadone

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 116 participants
Low

Morphine vs buprenorphine

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 113 participants
Moderate

Morphine vs dilute tincture of opium

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Low

Opioids vs clonidine

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Low

Opioids vs diazepam

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Opioids vs phenobarbital

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 166 participants
Low

Opioids vs Placebo, no intervention or usual care (with or without placebo)

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Very low

Opioids vs chlorpromazine

Length of hospital stay · newborn infants with opioid withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Silicone earplugs vs no earplugs

Days of initial hospitalisation · preterm or very low birth weight infants

1 finding from 1 review

Noise or sound management in the neonatal intensive care unit for preterm or very low birth weight infants 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low