What do systematic reviews say?

Erbium:YAG laser vs Air-abrasive device (Perio-Flow)

• Interventions for replacing missing teeth: treatment of peri‐implantitis 2012 · Cochrane All outcomes

  6 months
  After 6 months there were no complications.
  1 study · 42 participants
  GRADE not reported

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Er:YAG laser surface debridement before bone augmentation led to lower complications and side effects compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

• Interventions for replacing missing teeth: treatment of peri‐implantitis 2012 · Cochrane All outcomes

  6 months
  All patients experienced flap exposure during healing, not associated with infective complications; one patient had a slight pigmentation of the peri-implant soft tissues.
  1 study · 30 participants
  GRADE not reported

Metronidazole gel 25% (local antibiotic) vs Ultrasonic debridement

• Interventions for replacing missing teeth: treatment of peri‐implantitis 2012 · Cochrane All outcomes

  12 weeks
  No implant failures, complications or recurrence of peri-implantitis occurred in any of the groups.
  1 study · 27 participants
  GRADE not reported

Air-abrasive / Vector system debridement vs Manual debridement (carbon fibre curettes)

• Interventions for replacing missing teeth: treatment of peri‐implantitis 2012 · Cochrane All outcomes

  6 months
  No complications occurred in any of the groups.
  1 study · 11 participants
  GRADE not reported

Nanocrystalline hydroxyapatite (Ostim) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

• Interventions for replacing missing teeth: treatment of peri‐implantitis 2012 · Cochrane All outcomes

  6 months
  No complication occurred in any of the groups.
  1 study · 22 participants
  GRADE not reported

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Er:YAG laser debridement led to lower complications and side effects compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

• Interventions for replacing missing teeth: treatment of peri‐implantitis 2012 · Cochrane All outcomes

  6 months
  Complications: risk ratio (totals not selected); one laser patient had a buccal keratinised mucosa perforation.
  1 study · 20 participants
  GRADE not reported

Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox) added to manual debridement vs Manual debridement plus chlorhexidine irrigation/gel

• Interventions for replacing missing teeth: treatment of peri‐implantitis 2012 · Cochrane All outcomes

  4 months (18 weeks)
  No complications occurred in any of the groups.
  1 study · 28 participants
  GRADE not reported

Implant surface smoothening added to systemic antibiotics + resective surgery + local antibiotics vs No implant surface smoothening (same surgical protocol)

• Interventions for replacing missing teeth: treatment of peri‐implantitis 2012 · Cochrane All outcomes

  2 years
  No complications occurred in any of the groups.
  1 study · 17 participants
  GRADE not reported