Findings

What do systematic reviews say?

7 questions · 7 findings · 2 reviews · Eyes and Vision

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No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 3 · 42.9%Moderate 1 · 14.3%High 1 · 14.3%

Intraoperative 5‐Fluorouracil vs placebo or control

Complications ‐ shallow anterior chamber · participants with glaucoma surgery

Intraoperative 5‐Fluorouracil leads to higher complications ‐ shallow anterior chamber compared with placebo or control (high certainty).

1 finding from 1 review

5‐Fluorouracil for glaucoma surgery 2014 · Cochrane Headline outcomes only
RR 1.99 [1.22, 3.22]
4 studies · 711 participants
High

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ shallow anterior chamber · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ shallow anterior chamber compared with control (low certainty).

1 finding from 1 review

5‐Fluorouracil for glaucoma surgery 2014 · Cochrane Headline outcomes only
RR 1.84 [0.76, 4.46]
6 studies · 469 participants
Low

Low‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ shallow anterior chamber ‐ not reported · participants with glaucoma surgery

The review found no eligible studies for this question.

1 finding from 1 review

5‐Fluorouracil for glaucoma surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ shallow anterior chamber ‐ combined surgery · participants with glaucoma surgery

1 finding from 1 review

5‐Fluorouracil for glaucoma surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 118 participants
Very low

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ shallow anterior chamber ‐ high risk of failure · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ shallow anterior chamber ‐ high risk of failure compared with control (moderate certainty).

1 finding from 1 review

5‐Fluorouracil for glaucoma surgery 2014 · Cochrane Headline outcomes only
RR 2.41 [0.88, 6.58]
2 studies · 239 participants
Moderate

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ shallow anterior chamber ‐ primary trabeculectomy · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ shallow anterior chamber ‐ primary trabeculectomy compared with control (low certainty).

1 finding from 1 review

5‐Fluorouracil for glaucoma surgery 2014 · Cochrane Headline outcomes only
RR 0.47 [0.04, 4.91]
2 studies · 112 participants
Low

Intervention not reported

complications shallow anterior chamber occurring within 12 months · People undergoing trabeculectomy surgery with glaucoma

The intervention showed no clear difference in complications shallow anterior chamber occurring within 12 months (low certainty).

1 finding from 1 review

Intraoperative Mitomycin C for glaucoma surgery 2005 · Cochrane Headline outcomes only
RR 1.14 [0.42, 3.07]
10 studies · 441 participants
Low