What do systematic reviews say?

11 questions · 11 findings · 4 reviews · Oral Health

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No studies found 0 · 0%GRADE not reported 11 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Complications (adverse effects) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Intra-articular injection of sodium hyaluronate showed no clear difference in complications (adverse effects) compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

1 finding from 1 review

Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
RR 1.20 [0.44, 3.30]
1 study · 40 participants
GRADE not reported

Oral diclofenac sodium (NSAID) vs splint

Complications (adverse effects) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Diclofenac sodium (oral NSAID) showed no clear difference in complications (adverse effects) compared with occlusal splint therapy; GRADE not reported.

1 finding from 1 review

Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
RR 1.07 [0.50, 2.28]
1 study · 29 participants
GRADE not reported

Open surgical exposure vs Closed surgical exposure

Complications or adverse effects · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

1 finding from 1 review

Open versus closed surgical exposure of canine teeth that are displaced in the roof of the mouth 2017 · Cochrane All outcomes
Perioperative to alignment
SoF (Complications, no GRADE rating given): 'One surgical failure was due to detachment of the gold chain (closed group). One study reported two complications following surgery, both in the closed group: a…
1 study
GRADE not reported

ADMG + CAF vs CAF

Occurrence of adverse effects or postoperative complications · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

1 finding from 1 review

Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes
Short term (6 to 12 months)
Ahmedbeyli 2014: patients rated ADMG + CAF and CAF equally for pain during surgery, discomfort, postsurgical pain/swelling and complications
1 study
GRADE not reported

GTR rm + CAF vs SCTG + CAF

Occurrence of adverse effects or postoperative complications · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

1 finding from 1 review

Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes
Short term (6 to 12 months)
Wang 2001: two patients treated with SCTG experienced adverse effects (one postsurgical swelling, one postsurgical ecchymosis)
1 study
GRADE not reported

PRF + CAF vs SCTG + CAF

Occurrence of adverse effects or postoperative complications · Adult patients with multiple recession-type defects (Miller Class I/II, at least 3 mm)

1 finding from 1 review

Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes
Short term (6 to 12 months)
Oncu 2017: VAS showed less discomfort during the first postoperative week for PRF + CAF compared to SCTG + CAF
1 study
GRADE not reported

GTR rm associated with bone substitutes + CAF vs GTR rm + CAF

Occurrence of adverse effects or postoperative complications · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

1 finding from 1 review

Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes
Short term (6 to 12 months)
Dodge 2000: membrane exposure reported between the first and second weeks of healing
1 study
GRADE not reported

EMP + CAF vs SCTG + CAF

Occurrence of adverse effects or postoperative complications · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

1 finding from 1 review

Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes
McGuire 2012: patient-reported discomfort statistically significantly higher for SCTG than EMP + CAF, only at 1 month postoperatively
1 study
GRADE not reported

GTR rm + CAF vs GTR nrm + CAF

Occurrence of adverse effects or postoperative complications · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

1 finding from 1 review

Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes
Short term (6 to 12 months)
Roccuzzo 1996: membrane exposure reported between the first and second weeks of healing
1 study
GRADE not reported

XCM + CAF vs CAF

Occurrence of adverse effects or postoperative complications · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

1 finding from 1 review

Root coverage procedures for treating localised and multiple recession‐type defects 2018 · Cochrane All outcomes
Jepsen 2013: no differences regarding pain and discomfort between XCM + CAF and CAF (for all defects)
1 study
GRADE not reported

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Post-operative adverse events and complications · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

1 finding from 1 review

Guided tissue regeneration for periodontal infra-bony defects 2006 · Cochrane All outcomes
Adverse effects were generally minor. Healing was generally uneventful for both test and control groups. Exposure of the GTR barrier membrane was widely reported, ranging from 20% of sites (non-resorbable…
16 studies
GRADE not reported