Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

61 questions · 61 findings · 14 reviews · Oral Health

No studies found 1 · 1.6%GRADE not reported 52 · 85.2%Very low 4 · 6.6%Low 4 · 6.6%Moderate 0 · 0%High 0 · 0%

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Complications and side effects · People with at least one dental implant affected by perimplantitis

Er:YAG laser surface debridement before bone augmentation led to lower complications and side effects compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

1 finding from 1 review

One-stage lateral sinus lift with monocortical autogenous bone blocks (iliac crest) vs Two-stage lateral sinus lift with autogenous particulate bone (iliac crest)

Complication (perforation of sinus membrane) at augmented site · Patients with 2 to 7 mm of residual alveolar bone height in the edentulous maxillary sinus floor

One-stage lateral sinus lift with monocortical autogenous bone… showed no clear difference in complications (sinus membrane perforation) compared with two-stage lateral sinus lift with autogenous particulate bone (iliac…; GRADE not reported.

1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with allograft (bone graft) vs ARP with xenograft

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with alloplast vs Extraction alone

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with alloplast vs ARP with xenograft

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

Pilocarpine vs no treatment/placebo

Other oral related symptoms (oral discomfort, eating difficulty, mucosal pain, oral complications) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review

Autogenous bone graft (two-stage lateral sinus lift) vs Bone substitute (anorganic bovine bone / Bio-Oss)

Complications · Patients with an atrophic posterior maxilla requiring maxillary sinus augmentation

Autogenous bone graft (two-stage lateral sinus lift) showed no clear difference in complications compared with bone substitute (anorganic bovine bone / Bio-Oss); GRADE not reported.

1 finding from 1 review

Bone graft with platelet-rich plasma (PRP) vs Bone graft without PRP

Complications · Patients with insufficient bone below the maxillary sinus requiring dental implants
1 finding from 1 review

One-stage crestal-approach sinus lift with autogenous bone and 8 mm implants vs Lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and implants at least 10 mm long

Complications · Patients with 3 to 6 mm of residual bone height at the sinus floor

One-stage crestal-approach sinus lift with autogenous bone and 8 mm… showed no clear difference in complications compared with lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and…; GRADE not reported.

1 finding from 1 review

Osteotomes with mallet (Summers' technique) vs Rotary instruments (Cosci technique)

Complications · Patients undergoing crestal maxillary sinus lift

Osteotomes with mallet (Summers' technique) showed no clear difference in complications compared with rotary instruments (Cosci technique); GRADE not reported.

1 finding from 1 review

Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)

Complications · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height)

Sinus lift with bone graft (granular Bio-Oss) showed no clear difference in complications compared with sinus lift without bone graft (Inion resorbable rigid barrier…; GRADE not reported.

1 finding from 1 review

One-stage augmentation (implants placed simultaneously) vs Two-stage augmentation (delayed implant placement)

Complications · Patients with insufficient bone below the maxillary sinus requiring dental implants

One-stage augmentation (implants placed simultaneously) showed no clear difference in complications compared with two-stage augmentation (delayed implant placement); GRADE not reported.

1 finding from 1 review

Zygomatic implants without bone grafts (as a complete alternative to any bone augmentation procedure) vs Conventional dental implants in augmented maxillae

Complications · Participants with an atrophic maxilla who cannot be rehabilitated with conventional dental implants due to lack of bone (including…

The review found no eligible studies for this question.

1 finding from 1 review

Vertical distraction osteogenesis vs Autogenous inlay bone graft (iliac crest)

Complications · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical distraction osteogenesis showed no clear difference in complications compared with autogenous inlay bone graft (iliac crest); GRADE not reported.

1 finding from 1 review

Inlay autogenous bone graft (iliac crest) vs Inlay bone substitute (Bio-Oss block)

Major complications · Patients with atrophic posterior mandibles (5 to 7 mm above the mandibular canal) needing implants

Inlay autogenous bone graft (iliac crest) showed no clear difference in major complications compared with inlay bone substitute (Bio-Oss block); GRADE not reported.

1 finding from 1 review

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer implants (vertical augmentation) vs Short implants (8 to 11 mm) without augmentation

Major complications · Patients with atrophic (resorbed) mandibles needing implants

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to higher major complications compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.

1 finding from 1 review