Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Mixed action antidepressant vs placebo

Completion of scheduled treatment · cannabis dependence

Mixed action antidepressant showed no clear difference in completion of scheduled treatment compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 0.93 [0.71, 1.21]
2 studies · 169 participants
Low

Δ9‐Tetrahydrocannabinol preparation vs placebo

Completion of scheduled treatment · cannabis dependence

Δ9‐Tetrahydrocannabinol preparation showed no clear difference in completion of scheduled treatment compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 1.1 [0.88, 1.37]
4 studies · 369 participants
Low

Selective serotonin reuptake inhibitors vs placebo

Completion of scheduled treatment · cannabis dependence

It is very uncertain whether selective serotonin reuptake inhibitor antidepressant changes completion of scheduled treatment compared with placebo (very low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 0.79 [0.49, 1.27]
3 studies · 198 participants
Very low