Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Kidney and Transplant

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Calcineurin inhibitors ± steroids vs placebo/no treatment/supportive treatment/steroids

Complete remission · primary membranous nephropathy in adults with nephrotic syndrome

Calcineurin inhibitors ± steroids showed no clear difference in complete remission at final compared with placebo/no treatment/supportive treatment/steroids (low certainty).

1 finding from 1 review

Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome 2021 · Cochrane Headline outcomes only
RR 1.07 [0.51, 2.24]
5 studies · 206 participants
Low

Calcineurin inhibitors ± steroids vs alkylating agents ± steroids

Complete remission · primary membranous nephropathy in adults with nephrotic syndrome

Calcineurin inhibitors ± steroids showed no clear difference in complete remission at final compared with alkylating agents ± steroids (low certainty).

1 finding from 1 review

Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome 2021 · Cochrane Headline outcomes only
RR 1.15 [0.84, 1.56]
10 studies · 533 participants
Low