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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews · Schizophrenia

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%

Lithium vs antipsychotics

Clinically significant response on manic symptoms at least 50% Bech‐Rafaelsen improvement · schizophrenia

Lithium showed no clear difference in clinically significant response on manic symptoms at least 50%… compared with antipsychotics (low certainty).

1 finding from 1 review

Lithium as sole treatment vs placebo

Clinically significant response on manic symptoms at least 50% Bech‐Rafaelsen improvement · schizophrenia

Lithium as sole treatment showed no clear difference in clinically significant response on manic symptoms at least 50%… compared with placebo (low certainty).

1 finding from 1 review

Adjunctive lithium + antipsychotics vs placebo/no adjunctive treatment + antipsychotics

Clinically significant response on manic symptoms at least 50% Bech‐Rafaelsen improvement · schizophrenia

Adjunctive lithium + antipsychotics showed no clear difference in clinically significant response on manic symptoms at least 50%… compared with placebo/no adjunctive treatment + antipsychotics (low certainty).

1 finding from 1 review