Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 14 findings · 5 reviews · Gut

No studies found 1 · 7.1%GRADE not reported 0 · 0%Very low 3 · 21.4%Low 3 · 21.4%Moderate 4 · 28.6%High 3 · 21.4%

Inulin and oligofructose 15 g vs inulin and oligofructose 7.5 g daily

Clinical remission · Patients with active mild to moderate ulcerative colitis

It is very uncertain whether inulin and oligofructose 15 g changes clinical remission (9 weeks) compared with inulin and oligofructose 7.5 g daily (very low certainty).

1 finding from 1 review

Ustekinumab vs placebo

Failure to maintain remission · people with moderate to severe Crohn's disease in remission

Ustekinumab showed no clear difference in failure to maintain clinical remission compared with placebo (moderate certainty).

2 findings from 1 review

Oral 5‐ASA vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Failure to induce global or clinical remission · Patients with active mild to moderate ulcerative colitis

Oral 5‐ASA showed no clear difference in failure to induce global or clinical remission compared with comparator 5‐ASA (moderate certainty).

1 finding from 1 review