Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Musculoskeletal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

Rituximab (2 x 1000 mg) plus methotrexate vs methotrexate

ACR 50% improvement · patients with rheumatoid arthritis

Rituximab (2 x 1000 mg) plus methotrexate probably leads to higher clinical improvement American College of Rheumatology 50%… compared with methotrexate monotherapy (moderate certainty).

1 finding from 1 review

Rituximab for rheumatoid arthritis 2015 · Cochrane Headline outcomes only
RR 3.3 [2.3, 4.6]
4 studies · 1165 participants
Moderate