What do systematic reviews say?

Bismuth enema vs placebo

It is very uncertain whether bismuth enema changes clinical improvement compared with placebo (very low certainty).

• Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
  RR 1 [0.5, 1.98]
  1 study · 40 participants
  Very low