Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · All outcomes

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No studies found 0 · 0%GRADE not reported 2 · 40%Very low 1 · 20%Low 2 · 40%Moderate 0 · 0%High 0 · 0%

3Mix (ciprofloxacin + metronidazole + minocycline) vs simvastatin

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether 3Mix (ciprofloxacin + metronidazole + minocycline) changes clinical failure compared with simvastatin (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.00 [0.51, 1.95]
1 study · 160 participants
Very low

3Mix (ciprofloxacin + metronidazole + minocycline) vs 3Mixtatin

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

3Mix (ciprofloxacin + metronidazole + minocycline) may leads to higher clinical failure compared with 3Mixtatin (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 4.00 [1.22, 13.11]
1 study · 160 participants
Low

3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy vs 3Mix pulpectomy

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy showed no clear difference in clinical failure compared with 3Mix pulpectomy; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 5.00 [0.25, 99.95]
1 study · 60 participants
GRADE not reported

Mineral trioxide aggregate (MTA) vs 3Mix (ciprofloxacin + metronidazole + minocycline)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) may leads to lower clinical failure compared with 3Mix (ciprofloxacin + metronidazole + minocycline) (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.17 [0.04, 0.70]
1 study · 160 participants
Low

Vitapex (calcium hydroxide/iodoform) vs 3Mix (ciprofloxacin + metronidazole + minocycline)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with 3Mix (ciprofloxacin + metronidazole + minocycline); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.00 [0.07, 15.12]
1 study · 50 participants
GRADE not reported