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Evidence found and GRADE certainty

24 questions · 31 findings · 7 reviews · Oral Health

No studies found 1 · 3.2%GRADE not reported 16 · 51.6%Very low 6 · 19.4%Low 8 · 25.8%Moderate 0 · 0%High 0 · 0%

GTR rm associated with bone substitutes + CAF vs SCTG + CAF

Attachment change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

GTR rm associated with bone substitutes + CAF showed no clear difference in clinical attachment level change compared with SCTG + CAF; GRADE not reported.

1 finding from 1 review

GTR rm associated with bone substitutes + CAF vs GTR rm + CAF

Attachment change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

GTR rm associated with bone substitutes + CAF showed no clear difference in clinical attachment level change compared with GTR rm + CAF; GRADE not reported.

1 finding from 1 review

EMP + CAF vs CAF

Attachment change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

EMP + CAF showed no clear difference in clinical attachment level change compared with CAF (low certainty).

2 findings from 1 review

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Attachment change · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
1 finding from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

Attachment change · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… led to higher change in clinical attachment level (CAL) compared with subgingival instrumentation (SI) alone (hand or power-driven, or…; GRADE not reported.

2 findings from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

Attachment change · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care

It is very uncertain whether adjunctive antimicrobial photodynamic therapy (aPDT) applied after… changes change in clinical attachment level (CAL) compared with subgingival instrumentation (SI) alone (hand or power-driven, or… (very low certainty).

2 findings from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT

Attachment change · Adults (> 18 years) with peri-implant mucositis, receiving active treatment

The review found no eligible studies for this question.

1 finding from 1 review

Full-mouth scaling (FMS): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours, without antiseptic vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart

Attachment change · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

Full-mouth scaling (FMS): scaling/root planing (subgingival… showed no clear difference in change in clinical attachment level (CAL) compared with quadrant scaling and root planing (control): SRP of each quadrant in… (low certainty).

1 finding from 1 review

Full-mouth scaling (FMS): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours, without antiseptic vs Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing)

Attachment change · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

Full-mouth scaling (FMS): scaling/root planing (subgingival… showed no clear difference in change in clinical attachment level (CAL) compared with full-mouth disinfection (FMD): scaling/root planing (subgingival… (low certainty).

1 finding from 1 review

Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing) vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart

Attachment change · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

Full-mouth disinfection (FMD): scaling/root planing (subgingival… showed no clear difference in change in clinical attachment level (CAL) compared with quadrant scaling and root planing (control): SRP of each quadrant in… (low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in clinical attachment level (CAL) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).

3 findings from 1 review

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in clinical attachment level (CAL) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + open flap debridement (OFD) + bone graft (BG) vs OFD + BG (open flap debridement + bone graft)

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD)… changes change in clinical attachment level (CAL) (mm) compared with OFD + BG (open flap debridement + bone graft) (very low certainty).

3 findings from 1 review

Autologous platelet concentrates (APC) + open flap debridement (OFD) vs Open flap debridement (access flap surgery)

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in clinical attachment level (CAL) (mm) compared with OFD (open flap debridement) alone (very low certainty).

1 finding from 1 review