Findings

What do systematic reviews say?

2 questions · 4 findings · 1 reviews · Dental caries

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No studies found 0 · 0%GRADE not reported 3 · 75%Very low 0 · 0%Low 0 · 0%Moderate 1 · 25%High 0 · 0%

Biodentine vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…

Biodentine and calcium hydroxide did not differ significantly in clinical and radiographic success (OR 3.14, 95% CI 0.91 to 10.86; ungraded subgroup analysis).

1 finding from 1 review

Effectiveness of calcium hydroxide compared to hydraulic calcium silicate cements for direct pulp capping in managing… 2025 All outcomes
>=12 months · Primary or secondary dental care
OR 3.14 [0.91, 10.86]
3 studies · 242 participants
GRADE not reported

Hydraulic calcium silicate cements (HCSC; MTA or Biodentine) vs Calcium hydroxide (CH)

At 36-month follow-up, HCSC show higher odds of clinical and radiographic success than CaOH (OR 2.34, 95% CI 1.43 to 3.84; ungraded subgroup).

3 findings from 1 review

Effectiveness of calcium hydroxide compared to hydraulic calcium silicate cements for direct pulp capping in managing… 2025 All outcomes
36 months · Primary or secondary dental care · 36-month follow-up
OR 2.34 [1.43, 3.84]
2 studies · 379 participants
GRADE not reported
Effectiveness of calcium hydroxide compared to hydraulic calcium silicate cements for direct pulp capping in managing… 2025 All outcomes
12 months · Primary or secondary dental care · 12-month follow-up
OR 4.44 [1.63, 12.07]
3 studies · 174 participants
GRADE not reported
Effectiveness of calcium hydroxide compared to hydraulic calcium silicate cements for direct pulp capping in managing… 2025 All outcomes
>=12 months · Primary or secondary dental care
OR 2.68 [1.7, 4.22]
5 studies · 552 participants
Moderate