Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 4 reviews · Pregnancy and Childbirth

No studies found 2 · 20%GRADE not reported 0 · 0%Very low 1 · 10%Low 4 · 40%Moderate 1 · 10%High 2 · 20%

Betamethasone 12‐hourly vs 24‐hourly dosing – fetal/neonatal outcomes

Chronic lung disease · women at risk of preterm birth

It is very uncertain whether betamethasone 12‐hourly changes chronic lung disease compared with 24‐hourly dosing – fetal/neonatal outcomes (very low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Bronchopulmonary dysplasia/chronic lung disease · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in chronic lung disease/bronchopulmonary dysplasia (newborn/infant)** compared with placebo (outcomes (low certainty).

1 finding from 1 review

DCC with immediate neonatal care with cord intact vs ECC

Chronic lung disease · babies born preterm, and their mothers

DCC with immediate neonatal care with cord intact showed no clear difference in chronic lung disease (CLD) ‐ oxygen supplement at 36 weeks… compared with ECC (low certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs UCM

Chronic lung disease · babies born preterm, and their mothers

DCC with immediate neonatal care after cord clamping showed no clear difference in chronic lung disease (CLD) ‐ oxygen supplement at 36 weeks… compared with UCM (low certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs ECC (subgroup analysis by gestation)

Chronic lung disease · babies born preterm, and their mothers

DCC with immediate neonatal care after cord clamping showed no clear difference in chronic lung disease (CLD) ‐ oxygen supplement at 36 weeks… compared with ECC (subgroup analysis by gestation) (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Chronic lung disease · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A8: Chronic lung disease – all fetuses randomised compared with single course (high certainty).

1 finding from 1 review