Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Dementia and Cognitive Improvement

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

Change in global disease severity · Apathy in people with mild‐to‐moderate Alzheimer's disease

Methylphenidate showed no clear difference in change in global disease severity compared with placebo (moderate certainty).

1 finding from 1 review

Pharmacological interventions for apathy in Alzheimer's disease 2018 · Cochrane Headline outcomes only
RR 0.56 [0.15, 2.1]
2 studies · 85 participants
Moderate