Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Eyes and Vision

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No studies found 1 · 33.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%

Oral omega‐3 PUFAs plus conventional therapy vs conventional therapy

Aqueous tear production · people with dry eyea

The review found no eligible studies for this question.

1 finding from 1 review

Omega‐3 and omega‐6 polyunsaturated fatty acids for dry eye disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral long‐chain omega‐3 PUFAs vs oral omega‐6 PUFAs

Aqueous tear production · people with dry eyea

Oral long‐chain omega‐3 PUFAs showed no clear difference in change in Schirmer test (aqueous tear production, measured in mm/5… compared with oral omega‐6 PUFAs (low certainty).

1 finding from 1 review

Omega‐3 and omega‐6 polyunsaturated fatty acids for dry eye disease 2019 · Cochrane Headline outcomes only
MD 2.6
5 studies · 1205 participants
Low

Oral long‐chain omega‐3 PUFAs vs placebo or no treatment

Aqueous tear production · people with dry eyea

Oral long‐chain omega‐3 PUFAs (ie, EPA and DHA) showed no clear difference in change in Schirmer test (aqueous tear production, measured in mm/5… compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Omega‐3 and omega‐6 polyunsaturated fatty acids for dry eye disease 2019 · Cochrane Headline outcomes only
MD 0.68
7 studies · 1730 participants
Moderate