Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 10 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Placebo vs no treatment

Caries increment in permanent teeth · Children or adolescents

The NMR reported an SMD by randomisation year; no GRADE assessment was reported.

1 finding from 1 review

Placebo vs no treatment

Caries increment, surface index D(M)FS · Children or adolescents

In the illustrative network meta-regression the SMD for caries increment differed between placebo and no treatment at randomization years 1970 to 1990; certainty was not graded.

1 finding from 1 review

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs placebo

Caries increment in permanent teeth · Children or adolescents

The NMR reported a difference between fluoride in gel and placebo at randomisation years 1954 to 1980; no GRADE assessment was reported.

1 finding from 1 review

Fluoride in dentifrice vs placebo

Caries increment, surface index D(M)FS · Children or adolescents

In the illustrative network meta-regression the SMD for caries increment differed between fluoride in dentifrice and placebo at every displayed randomization year; certainty was not graded.

1 finding from 1 review

Fluoride in rinse vs placebo

Caries increment, surface index D(M)FS · Children or adolescents

In the illustrative network meta-regression the SMD for caries increment differed between fluoride in rinse and placebo at randomization years 1954 to 1990; certainty was not graded.

1 finding from 1 review

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs placebo

Caries increment, surface index D(M)FS · Children or adolescents

In the illustrative network meta-regression the SMD for caries increment differed between fluoride in gel and placebo at randomization years 1954 to 1980; certainty was not graded.

1 finding from 1 review

Fluoride varnish vs placebo

Caries increment, surface index D(M)FS · Children or adolescents

In the illustrative network meta-regression the SMD for caries increment showed a treatment-by-year interaction and differed between fluoride in varnish and placebo at randomization years 1954 to 1980; certainty was not graded.

1 finding from 1 review