Fluoride varnish vs Fissure sealant (resin-based or glass ionomer)
Caries incidence of occlusal surfaces of first permanent molars · Generally healthy children aged 6 to 9 years with at least one fully erupted first permanent molar with deep fissures or early enamel…
After excluding Bravo 1996, occlusal caries incidence slightly favored fluoride varnish but was not significant, with heterogeneity falling to 0% (RR 0.98, 95% CI 0.82 to 1.16; 3 RCTs; ungraded).
2 findings from 1 review
- Comparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a Systematic… 2020 All outcomes2 to 3 years · Sensitivity analysis excluding Bravo 1996 (high risk of bias)RR 0.98 [0.82, 1.16]3 studiesGRADE not reported
- Comparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a Systematic… 2020 All outcomes2 to 3 yearsRR 1.33 [0.83, 2.11]4 studies · 6551 participantsGRADE not reported