Fluoride varnish vs Fissure sealant (resin-based or glass ionomer)
Caries incidence of first permanent molars (FPMs) · Generally healthy children aged 6 to 9 years with at least one fully erupted first permanent molar with deep fissures or early enamel…
After excluding the high-risk-of-bias study (Bravo 1996), fluoride varnish and fissure sealant did not differ in caries incidence of FPMs and heterogeneity fell to 0% (RR 1.05, 95% CI 0.91 to 1.22; 5 RCTs; ungraded).
3 findings from 1 review
- Comparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a Systematic… 2020 All outcomes2 to 3 years · Sensitivity analysis excluding Bravo 1996 (high risk of bias)RR 1.05 [0.91, 1.22]5 studiesGRADE not reported
- Comparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a Systematic… 2020 All outcomes2 to 3 yearsRR 1.29 [0.95, 1.75]6 studies · 6878 participantsGRADE not reported
- Comparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a Systematic… 2020 All outcomes2 to 3 years · Sensitivity analysis excluding split-mouth design (Raadal 1984)RR 1.29 [0.88, 1.87]5 studiesGRADE not reported