Findings

What do systematic reviews say?

5 questions · 5 findings · 3 reviews

No studies found 1 · 20%GRADE not reported 0 · 0%Very low 1 · 20%Low 1 · 20%Moderate 1 · 20%High 1 · 20%

Cardiovascular events · people with or without existing cardiovascular disease, men and women

Higher polyunsaturated fatty acid (PUFA) showed no clear difference in cardiovascular events compared with lower PUFA (moderate certainty).

1 finding from 1 review

Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease 2018 · Cochrane Headline outcomes only
RR 0.89 [0.79, 1.01]
21 studies · 17799 participants
Moderate

Serious adverse events: cardiovascular events · dialysis vascular access outcomes in AVG patients with ESKD

It is very uncertain whether omega‐3 fatty acids changes serious adverse events: cardiovascular events compared with placebo (very low certainty).

1 finding from 1 review

Omega‐3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 261 participants
Very low

Serious adverse events: cardiovascular events · Dialysis vascular access outcomes in AVF patients with ESKD

The review found no eligible studies for this question.

1 finding from 1 review

Omega‐3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cardiovascular events · adults with or without existing CVD

High showed no clear difference in cardiovascular events compared with low alpha‐linolenic acid omega‐3 fats (low certainty).

1 finding from 1 review

Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease 2020 · Cochrane Headline outcomes only
RR 0.95 [0.83, 1.07]
5 studies · 19327 participants
Low

Cardiovascular events · adults with or without existing CVD

High showed no clear difference in cardiovascular events compared with low long‐chain omega‐3 fats (high certainty).

1 finding from 1 review

Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease 2020 · Cochrane Headline outcomes only
RR 0.96 [0.92, 1.01]
43 studies · 140482 participants
High