Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Headline outcomes only

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No studies found 1 · 20%GRADE not reported 0 · 0%Very low 2 · 40%Low 2 · 40%Moderate 0 · 0%High 0 · 0%

Surgery vs radiofrequency ablation

Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma eligible for surgery

Surgery may leads to lower cancer‐related mortality at maximal compared with radiofrequency ablation (low certainty).

1 finding from 1 review

Management of people with early‐ or very early‐stage hepatocellular carcinoma 2017 · Cochrane Headline outcomes only
OR 0.35 [0.19, 0.65]
1 study · 230 participants
Low

Laser ablation vs radiofrequency ablation

Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether laser ablation changes cancer‐related mortality at maximal compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Management of people with early‐ or very early‐stage hepatocellular carcinoma 2017 · Cochrane Headline outcomes only
OR 1.26 [0.49, 3.27]
1 study · 140 participants
Very low

Transarterial embolisation plus radiofrequency ablation vs radiofrequency ablation

Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

The review found no eligible studies for this question.

1 finding from 1 review

Management of people with early‐ or very early‐stage hepatocellular carcinoma 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transarterial embolisation plus percutaneous alcohol injection vs percutaneous alcohol injection

Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether transarterial embolisation plus percutaneous alcohol injection changes cancer‐related mortality at maximal compared with percutaneous alcohol injection (very low certainty).

1 finding from 1 review

Management of people with early‐ or very early‐stage hepatocellular carcinoma 2017 · Cochrane Headline outcomes only
OR 0.07 [0, 1.41]
1 study · 52 participants
Very low

Percutaneous ethanol injection vs radiofrequency ablation

Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

Percutaneous alcohol injection may leads to higher cancer‐related mortality at maximal compared with radiofrequency ablation (low certainty).

1 finding from 1 review

Management of people with early‐ or very early‐stage hepatocellular carcinoma 2017 · Cochrane Headline outcomes only
OR 2.18 [1.22, 3.89]
3 studies · 458 participants
Low