Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Kidney and Transplant

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 40%Moderate 2 · 40%High 1 · 20%

CMV disease · solid organ transplant recipients

Ganciclovir leads to lower CMV disease compared with aciclovir (high certainty).

1 finding from 1 review

Death associated with CMV disease · solid organ transplant recipients

Ganciclovir showed no clear difference in death due to CMV disease compared with aciclovir (moderate certainty).

1 finding from 1 review

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients 2024 · Cochrane Headline outcomes only
RR 0.33 [0.07, 1.58]
6 studies · 832 participants
Moderate

CMV disease · solid organ transplant recipients

Valaciclovir showed no clear difference in CMV disease compared with ganciclovir or valganciclovir (low certainty).

1 finding from 1 review

CMV disease · solid organ transplant recipients

Extended probably leads to lower CMV disease compared with short‐duration valganciclovir (moderate certainty).

1 finding from 1 review

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients 2024 · Cochrane Headline outcomes only
RR 0.2 [0.12, 0.35]
2 studies · 454 participants
Moderate

CMV disease · solid organ transplant recipients

Maribavir showed no clear difference in CMV disease compared with ganciclovir (low certainty).

1 finding from 1 review