Evidence Gaps

What do systematic reviews say?

1 questions · 3 findings · 1 reviews · Dental caries

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No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Higher circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower circulating 25-hydroxyvitamin D (25(OH)D) concentration

Breast cancer · Adults (general population)

Meta-analysis of observational studies (higher vs lower 25(OH)D) for Breast cancer (Premenopausal): RR 1.01 (95% CI 0.97 to 1.06), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.

3 findings from 1 review

Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational… 2014 All outcomes
Premenopausal
RR 1.01 [0.97, 1.06]
6 studies · 2890 participants
GRADE not reported
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational… 2014 All outcomes
Postmenopausal
RR 0.99 [0.97, 1.01]
9 studies · 8766 participants
GRADE not reported
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational… 2014 All outcomes
OR 0.55 [0.42, 0.71]
21 studies · 26317 participants
GRADE not reported