Grape seed extract (GSE) and its proanthocyanidin fractions vs Untreated or vehicle control (some studies vs positive antimicrobial controls, e.g. chlorhexidine/fluoride)
Bacterial growth inhibition · Streptococcus mutans (in vitro cultures and biofilms)
Grape seed extract inhibits S. mutans growth in vitro (MIC ~0.5 mg/mL to 250 mg/mL across 5 studies; ungraded).
1 finding from 1 review
- Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a… 2024 All outcomesin vitro (laboratory)GSE inhibited S. mutans growth across ~0.5-250 mg/mL (Abstract): inhibition at 250-500 mg/mL (Swadas), 4 mg/mL (Zhao), MIC 1000 ug/mL and MBC 4000 ug/mL (Furiga), MIC 0.5 mg/mL (Smullen), and MIC 19.07 mg/mL for…5 studiesGRADE not reported