Caries-associated bacterial biofilm vs Sound/control tissue (sound dentin, sound root, or enamel caries)
Bacterial collagenolytic protease gene expression · Human ex vivo carious lesions / caries-associated biofilm
Genes encoding bacterial collagenolytic proteases were detected/overexpressed in coronal and root caries (ungraded; GRADE not feasible).
1 finding from 1 review
- Presence of host and bacterial-derived collagenolytic proteases in carious dentin: a systematic review of ex vivo… 2023 All outcomesEx vivo (extracted teeth / clinical carious or biofilm samples)Genes coding for bacterial collagenolytic proteases were significantly expressed/overrepresented in coronal (Simon-Soro et al., 2013) and root (Dame-Teixeira et al., 2018: 42 proteases differentially expressed, 18…2 studies · 25 participantsGRADE not reported