What do systematic reviews say?

High initial concentration vs low initial concentration

High initial concentration may leads to higher apneoa compared with low initial concentration (low certainty).

• High initial concentration versus low initial concentration sevoflurane for inhalational induction of anaesthesia 2016 · Cochrane Headline outcomes only
  RR 3.14 [1.72, 5.7]
  2 studies · 160 participants
  Low