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What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Topical prophylaxis vs no topical prophylaxis

Allergic adverse events · adults receiving mechanical ventilation for at least 48 hours

It is very uncertain whether topical prophylaxis changes allergic adverse events compared with no topical prophylaxis (very low certainty).

1 finding from 1 review

Topical plus systemic prophylaxis vs placebo or no treatment

Allergic adverse events · adults receiving mechanical ventilation for at least 48 hours

Topical plus systemic prophylaxis showed no clear difference in allergic adverse events compared with placebo or no treatment (low certainty).

1 finding from 1 review