Findings

What do systematic reviews say?

6 questions · 6 findings · 2 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 83.3%Moderate 1 · 16.7%High 0 · 0%

ICU mortality · people admitted to intensive care units

Proton pump inhibitors showed no clear difference in all‐cause mortality in ICU compared with placebo or no prophylaxis (low certainty).

1 finding from 1 review

ICU mortality · people admitted to intensive care units

Antacids showed no clear difference in all‐cause mortality in ICU compared with placebo or no prophylaxis (low certainty).

1 finding from 1 review

ICU mortality · people admitted to intensive care units

Sucralfate showed no clear difference in all‐cause mortality in ICU compared with placebo or no prophylaxis (low certainty).

1 finding from 1 review

ICU mortality · people admitted to intensive care units

Interventions showed no clear difference in all‐cause mortality in ICU compared with placebo or no prophylaxis (low certainty).

1 finding from 1 review

ICU mortality · people admitted to intensive care units

H2 receptor antagonists showed no clear difference in all‐cause mortality in ICU compared with placebo or no prophylaxis (low certainty).

1 finding from 1 review

ICU mortality · exacerbations of COPD

Antibiotics probably leads to lower all‐cause mortality ‐ ICU patients compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics for exacerbations of chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes only
OR 0.21 [0.06, 0.72]
1 study · 93 participants
Moderate