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What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 5 findings · 1 reviews · Injuries

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 1 · 20%High 1 · 20%

FIBRINOGEN: Therapeutic trials: intervention vs inactive control

All‐cause mortality Up to 28 days post‐operatively · the prevention and treatment of bleeding in patients without haemophilia

FIBRINOGEN: Therapeutic trials: intervention showed no clear difference in all‐cause mortality Up to 46 days post‐operatively compared with inactive Control (high certainty).

1 finding from 1 review

FIBRINOGEN: Therapeutic trials: intervention vs haemostatically active control

All‐cause mortality Up to 28 days post‐operatively · the prevention and treatment of bleeding in patients without haemophilia
2 findings from 1 review

FIBRINOGEN: Therapeutic trials: intervention vs inactive control

All‐cause mortality In‐hospital mortality up to 30 days post‐operatively · the prevention and treatment of bleeding in patients without haemophilia

FIBRINOGEN: Therapeutic trials: intervention showed no clear difference in all‐cause mortality In‐hospital mortality up to 30 days… compared with inactive Control (low certainty).

1 finding from 1 review